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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   IFIT1 Antibody - C-terminal region   

IFIT1 Antibody - C-terminal region

Rabbit Polyclonal Antibody

  • WB - IFIT1 Antibody - C-terminal region AI14695

    WB Suggested Anti-IFIT1 Antibody Titration: 1.0 μg/ml
    Positive Control: Fetal Stomach
  • WB - IFIT1 Antibody - C-terminal region AI14695

    WB Suggested Anti-IFIT1 Antibody
    Positive Control: Lane1: 30ug human Huh7, Lane2: 30ug human Huh7+IFNB stimulated
    Primary Antibody Dilution : 1:1000
    Secondary Antibody : Anti-rabbit-HRP
    Secondry Antibody Dilution : 1:5000
    Submitted by: Takeshi Saito, USC Keck School of Medicine
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P09914
Other Accession NM_001548, NP_001539
Reactivity Human
Predicted Human
Host Rabbit
Clonality Polyclonal
Calculated MW 55kDa
Additional Information
Gene ID 3434
Alias Symbol C56, G10P1, GARG-16, IFI-56, IFI56, IFNAI1, ISG56, RNM561
Other Names Interferon-induced protein with tetratricopeptide repeats 1, IFIT-1, Interferon-induced 56 kDa protein, IFI-56K, P56, IFIT1, G10P1, IFI56, IFNAI1, ISG56
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-IFIT1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsIFIT1 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name IFIT1
Synonyms G10P1, IFI56, IFNAI1, ISG56
Function Interferon-induced antiviral RNA-binding protein that specifically binds single-stranded RNA bearing a 5'-triphosphate group (PPP-RNA), thereby acting as a sensor of viral single- stranded RNAs and inhibiting expression of viral messenger RNAs. Single-stranded PPP-RNAs, which lack 2'-O-methylation of the 5' cap and bear a 5'-triphosphate group instead, are specific from viruses, providing a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Directly binds PPP-RNA in a non-sequence-specific manner. Viruses evolved several ways to evade this restriction system such as encoding their own 2'-O-methylase for their mRNAs or by stealing host cap containing the 2'-O-methylation (cap snatching mechanism). Exhibits antiviral activity against several viruses including human papilloma and hepatitis C viruses.
Cellular Location Cytoplasm
Research Areas
Citations (0)

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Wathelet M.,et al.Eur. J. Biochem. 155:11-17(1986).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Deloukas P.,et al.Nature 429:375-381(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.

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$ 293.00
Cat# AI14695
(40 western blots)
Availability: 2-3 days
Bulk Size
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