|Other Accession||NM_001175, NP_001166|
|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog|
|Alias Symbol||D4, GDIA2, GDID4, LYGDI, Ly-GDI, RAP1GN1, RhoGDI2|
|Other Names||Rho GDP-dissociation inhibitor 2, Rho GDI 2, Ly-GDI, Rho-GDI beta, ARHGDIB, GDIA2, GDID4, RAP1GN1|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-ARHGDIB antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||ARHGDIB Antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||GDIA2, GDID4, RAP1GN1|
|Function||Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them (PubMed:8356058, PubMed:7512369). Regulates reorganization of the actin cytoskeleton mediated by Rho family members (PubMed:8262133).|
|Cellular Location||Cytoplasm, cytosol|
|Tissue Location||Detected in bone marrow, thymus and spleen.|
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Provided below are standard protocols that you may find useful for product applications.
Scherle P.,et al.Proc. Natl. Acad. Sci. U.S.A. 90:7568-7572(1993).
Leffers H.,et al.Exp. Cell Res. 209:165-174(1993).
Lelias J.M.,et al.Proc. Natl. Acad. Sci. U.S.A. 90:1479-1483(1993).
Puhl H.L. III,et al.Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases.
Goshima N.,et al.Nat. Methods 5:1011-1017(2008).
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