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CKAP2 antibody - C-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q8WWK9 |
| Other Accession | NM_001098525, NP_001091995 |
| Reactivity | Human, Rat, Rabbit, Horse, Bovine, Guinea Pig, Dog |
| Predicted | Human, Pig, Horse, Bovine, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 77kDa |
| Gene ID | 26586 |
|---|---|
| Alias Symbol | DKFZp686L1238, FLJ10749, LB1, TMAP, se20-10 |
| Other Names | Cytoskeleton-associated protein 2, CTCL tumor antigen se20-10, Tumor- and microtubule-associated protein, CKAP2 (HGNC:1990) |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-CKAP2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | CKAP2 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CKAP2 (HGNC:1990) |
|---|---|
| Function | Possesses microtubule stabilizing properties. Involved in regulating aneuploidy, cell cycling, and cell death in a p53/TP53- dependent manner (By similarity). |
| Cellular Location | Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Note=Contrary to the ectopically expressed protein, endogenous CKAP2 does not colocalize with microtubules in G1, S and early G2. At late G2 and prophase after separation of duplicated centrosomes, colocalizes with gamma-tubulin and centrosome-proximal microtubules. From prometaphase through anaphase B, colocalizes with mitotic spindle poles and spindle microtubules. During cytokinesis, absent from midbody microtubules |
| Tissue Location | Abundant in testis, thymus, and in tumor derived cell lines, while barely detectable in liver, prostate, and kidney |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
Maouche-Chretien L.,et al.Oncogene 17:1245-1251(1998).
Udina I.G.,et al.Genetika 37:120-123(2001).
Bae C.-D.,et al.J. Cancer Res. Clin. Oncol. 129:621-630(2003).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
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