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>   home   >   Products   >   Primary Antibodies   >   Neuroscience   >   Cdk14 antibody - C-terminal region   

Cdk14 antibody - C-terminal region

Rabbit Polyclonal Antibody

  • WB - Cdk14 antibody - C-terminal region AI14749

    WB Suggested Anti-Cdk14 Antibody Titration: 1.0 μg/ml
    Positive Control: Mouse Pancreas
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O35495
Other Accession NM_011074, NP_035204
Reactivity Human, Mouse, Rat, Rabbit, Pig, Horse, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Rabbit, Pig, Chicken, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 53kDa
Additional Information
Gene ID 18647
Alias Symbol Pftk1, mKIAA0834
Other Names Cyclin-dependent kinase 14,, Cell division protein kinase 14, Serine/threonine-protein kinase PFTAIRE-1, Cdk14, Kiaa0834, Pftk1
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Cdk14 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsCdk14 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Cdk14
Synonyms Kiaa0834, Pftk1
Function Serine/threonine-protein kinase involved in the control of the eukaryotic cell cycle, whose activity is controlled by an associated cyclin. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by mediating the phosphorylation of LRP6 at 'Ser-1490', leading to the activation of the Wnt signaling pathway. Acts as a regulator of cell cycle progression and cell proliferation via its interaction with CCDN3. Phosphorylates RB1 in vitro, however the relevance of such result remains to be confirmed in vivo. May also play a role in meiosis, neuron differentiation and may indirectly act as a negative regulator of insulin-responsive glucose transport (By similarity).
Cellular Location Cell membrane; Peripheral membrane protein. Cytoplasm. Nucleus. Note=Recruited to the cell membrane by CCNY.
Tissue Location In the adult, widely expressed at low levels except in brain, kidney and testis where expression is high. In the brain, detected in cortex, hippocampus, dentate gyrus, amygdala cortex, parasubiculum and cerebellum. In the embryo, expressed predominantly in the nervous system
Research Areas
Citations (0)

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Besset V.,et al.Mol. Reprod. Dev. 50:18-29(1998).
Lazzaro M.A.,et al.J. Neurochem. 69:348-364(1997).
Carninci P.,et al.Science 309:1559-1563(2005).
Okazaki N.,et al.DNA Res. 10:167-180(2003).

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$ 293.00
Cat# AI14749
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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