|Other Accession||NM_201628, NP_963922|
|Reactivity||Human, Mouse, Rat, Rabbit, Horse, Dog|
|Predicted||Human, Mouse, Rat, Rabbit, Horse, Dog|
|Alias Symbol||KAZ, FLJ10199, FLJ32593, FLJ43398, FLJ43806, KIAA1026, MGC126686, MGC142181, RP1-21O18.1, DKFZp686D08115|
|Other Names||Kazrin, KAZN, KAZ, KIAA1026|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-FLJ43806 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||FLJ43806 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Component of the cornified envelope of keratinocytes. May be involved in the interplay between adherens junctions and desmosomes. The function in the nucleus is not known.|
|Cellular Location||Cytoplasm, cytoskeleton. Isoform 3: Cytoplasm. Cell junction, desmosome. Nucleus. Note=Observed at the apical plasma membrane of keratinocytes. Partially colocalizes with PPL and DP at desmosomes, and with PP at the interdesmosomal plasma membrane Colocalizes with cortical actin-based membrane structures|
|Tissue Location||Isoform 2, isoform 3 and isoform 4 are expressed in several cell lines including keratinocytes and bladder and epidermoid carcinoma (at protein level). Isoform 2, isoform 3 and isoform 4 are expressed in hair follicle and interfollicular epidermis (at protein level)|
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Provided below are standard protocols that you may find useful for product applications.
Groot K.R.,et al.J. Cell Biol. 166:653-659(2004).
Kikuno R.,et al.DNA Res. 6:197-205(1999).
Gregory S.G.,et al.Nature 441:315-321(2006).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Ueki N.,et al.Nat. Biotechnol. 16:1338-1342(1998).
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