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GRINL1A antibody - C-terminal region

Rabbit Polyclonal Antibody

     
  • WB - GRINL1A antibody - C-terminal region AI14793

    WB Suggested Anti-GRINL1A Antibody Titration: 1.0 μg/ml
    Positive Control: Placenta
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession P0CAP2
Other Accession NM_015532, NP_056347
Reactivity Human, Mouse, Rat, Rabbit, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Rabbit, Pig, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 40kDa
Additional Information
Gene ID 81488
Alias Symbol DKFZp586F1918, GCOM1, Gdown, Gdown1, GRINL1A
Other Names DNA-directed RNA polymerase II subunit GRINL1A, DNA-directed RNA polymerase II subunit M, Glutamate receptor-like protein 1A, POLR2M, GRINL1A
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-GRINL1A antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsGRINL1A antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name POLR2M
Synonyms GRINL1A
Function [Isoform 1]: Appears to be a stable component of the Pol II(G) complex form of RNA polymerase II (Pol II). Pol II synthesizes mRNA precursors and many functional non-coding RNAs and is the central component of the basal RNA polymerase II transcription machinery. May play a role in the Mediator complex-dependent regulation of transcription activation. Acts as a negative regulator of transcriptional activation; this repression is relieved by the Mediator complex, which restores Pol II(G) activator-dependent transcription to a level equivalent to that of Pol II.
Cellular Location [Isoform 1]: Nucleus.
Tissue Location Detected in adult an fetal brain. Detected in heart, kidney, skeletal muscle, small intestine, lung, prostate and testis.
Research Areas
Citations (0)
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References

Roginski R.S.,et al.Cytogenet. Cell Genet. 93:143-144(2001).
Roginski R.S.,et al.Genomics 84:265-276(2004).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Zody M.C.,et al.Nature 440:671-675(2006).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.

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$ 389.00
Cat# AI14793
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