|Other Accession||NM_030570, NP_085047|
|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Goat, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Human, Mouse, Rabbit, Pig, Bovine, Guinea Pig, Dog|
|Alias Symbol||C11orf23, DKFZp781E17107, DKFZp781E2374, DKFZp781O2362, FLJ11058, FLJ43065, KIAA1558, MGC125711, MGC125712, PP6R3, SAP190, SAPL, SAPLa, SAPS3|
|Other Names||Uroplakin-3b, UP3b, Uroplakin IIIb, UPIIIb, p35, UPK3B|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-PPP6R3 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||PPP6R3 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx which may play an important role in preventing bacterial adherence (By similarity).|
|Cellular Location||Cell membrane; Single-pass type I membrane protein. Note=Heterodimer formation with UPK1B is a prerequisite to exit out of the endoplasmic reticulum (ER).|
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Provided below are standard protocols that you may find useful for product applications.
Deng F.-M.,et al.J. Cell Biol. 159:685-694(2002).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 424:157-164(2003).
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