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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   SIRPG antibody - middle region   

SIRPG antibody - middle region

Rabbit Polyclonal Antibody

     
  • WB - SIRPG antibody - middle region AI14835

    WB Suggested Anti-SIRPG Antibody Titration: 1.0 μg/ml
    Positive Control: 293T Whole Cell
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession O75131
Other Accession NM_003909, NP_003900
Reactivity Human, Horse, Bovine
Predicted Human, Bovine
Host Rabbit
Clonality Polyclonal
Calculated MW 27kDa
Additional Information
Gene ID 8895
Alias Symbol CD172g, FLJ42230, SIRP-B2, SIRPB2, SIRPgamma, bA77C3.1
Other Names Copine-3, Copine III, CPNE3, CPN3, KIAA0636
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-SIRPG antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsSIRPG antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CPNE3 (HGNC:2316)
Function Calcium-dependent phospholipid-binding protein that plays a role in ERBB2-mediated tumor cell migration in response to growth factor heregulin stimulation (PubMed:20010870).
Cellular Location Nucleus. Cytoplasm. Cell membrane. Cell junction. Cell junction, focal adhesion. Note=Associates to the membrane in a calcium-dependent manner (PubMed:20010870) Translocates to the cell membrane and the nucleus in a calcium- or growth factor heregulin-dependent manner (PubMed:21087455, PubMed:20010870). Colocalizes with the tyrosine phosphorylated ERBB2 form at cell membrane and focal adhesions in a calcium- or growth factor heregulin-dependent manner (PubMed:20010870)
Tissue Location Expressed in breast and weakly in prostate and ovarian tissues (PubMed:20010870). Expressed in neutrophils (at protein level) (PubMed:12949241). Widely expressed (PubMed:11041869). Expressed in the brain. Expressed in neutrophil precursors from the bone marrow and peripheral blood (PubMed:12949241). Expressed in primary breast tumors and ovarian endometrioid adenocarcinoma (PubMed:20010870)
Research Areas
Citations (0)

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References

Caudell E.G.,et al.Biochemistry 39:13034-13043(2000).
Ishikawa K.,et al.DNA Res. 5:169-176(1998).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Dephoure N.,et al.Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Burkard T.R.,et al.BMC Syst. Biol. 5:17-17(2011).

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$ 293.00
Cat# AI14835
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