|Other Accession||NM_001042388, NP_001035847|
|Reactivity||Human, Rabbit, Pig, Horse, Dog|
|Predicted||Human, Rabbit, Pig, Horse, Dog|
|Alias Symbol||PP4(Rmeg), PP4R1|
|Other Names||Serine/threonine-protein phosphatase 4 regulatory subunit 1, PPP4R1, MEG1, PP4R1|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-PPP4R1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||PPP4R1 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Regulatory subunit of serine/threonine-protein phosphatase 4. May play a role in regulation of cell division in renal glomeruli. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3.|
|Tissue Location||Widely expressed with high expression in cultured mesangial cells. Isoform 1 and isoform 2 are expressed in renal tissues.|
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Provided below are standard protocols that you may find useful for product applications.
Kloeker S.,et al.J. Biol. Chem. 274:5339-5347(1999).
Wada T.,et al.J. Am. Soc. Nephrol. 12:2601-2608(2001).
Nusbaum C.,et al.Nature 437:551-555(2005).
Song H.,et al.Submitted (OCT-1998) to the EMBL/GenBank/DDBJ databases.
Yu W.,et al.Genome Res. 7:353-358(1997).
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