|Other Accession||NM_005191, NP_005182|
|Alias Symbol||CD28LG, CD28LG1, LAB7, B7, BB1, B7-1, B7.1|
|Other Names||T-lymphocyte activation antigen CD80, Activation B7-1 antigen, BB1, CTLA-4 counter-receptor B7.1, B7, CD80, CD80, CD28LG, CD28LG1, LAB7|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-CD80 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||CD80 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||CD28LG, CD28LG1, LAB7|
|Function||Involved in the costimulatory signal essential for T- lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation.|
|Cellular Location||Membrane; Single-pass type I membrane protein|
|Tissue Location||Expressed on activated B-cells, macrophages and dendritic cells|
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Provided below are standard protocols that you may find useful for product applications.
Freeman G.J.,et al.J. Immunol. 143:2714-2722(1989).
Selvakumar A.,et al.Immunogenetics 36:175-181(1992).
Kakoulidou M.,et al.Scand. J. Immunol. 66:529-537(2007).
Muzny D.M.,et al.Nature 440:1194-1198(2006).
Freeman G.J.,et al.J. Exp. Med. 174:625-631(1991).
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