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BROX Antibody - C-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q5VW32 |
| Other Accession | NP_653296 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 45kDa |
| Gene ID | 148362 |
|---|---|
| Alias Symbol | BROX, BROFTI, C1orf58, |
| Other Names | BRO1 domain-containing protein BROX, BRO1 domain- and CAAX motif-containing protein, BROX, BROFTI, C1orf58 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 &mu, l of distilled water. Final Anti-BROX antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | BROX Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | BROX (HGNC:26512) |
|---|---|
| Synonyms | BROFTI, C1orf58 |
| Function | Nuclear envelope-associated factor that is involved in the nuclear envelope ruptures during interphase (NERDI) repair, where it is locally recruited by CHMP5 and reduces cytoskeletal stress through its action on SYN2 to help reseal the ruptured membrane. |
| Cellular Location | Nucleus membrane; Lipid-anchor. Note=During nuclear envelope repair, localizes at rupture sites where it is recruited by the CHMP7/ESCRT-III axis. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
References
Ichioka F.,et al.FEBS J. 275:682-692(2008).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Gregory S.G.,et al.Nature 441:315-321(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Maurer-Stroh S.,et al.PLoS Comput. Biol. 3:634-648(2007).
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