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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   CYP4F2 antibody - C-terminal region   

CYP4F2 antibody - C-terminal region

Rabbit Polyclonal Antibody

  • WB - CYP4F2 antibody - C-terminal region AI15007

    WB Suggested Anti-CYP4F2 Antibody Titration: 1.0 μg/ml
    Positive Control: HepG2 Whole CellCYP4F2 is strongly supported by BioGPS gene expression data to be expressed in Human HepG2 cells
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P78329
Other Accession NM_001082, NP_001073
Reactivity Human, Mouse, Rat, Rabbit, Goat, Sheep, Horse, Bovine, Guinea Pig, Dog
Predicted Human, Pig, Sheep, Bovine
Host Rabbit
Clonality Polyclonal
Calculated MW 60kDa
Additional Information
Gene ID 8529
Alias Symbol CPF2
Other Names Phylloquinone omega-hydroxylase CYP4F2,, 20-hydroxyeicosatetraenoic acid synthase, 20-HETE synthase, 1.14.13.-, Arachidonic acid omega-hydroxylase, CYPIVF2, Cytochrome P450 4F2, Cytochrome P450-LTB-omega, Leukotriene-B(4) 20-monooxygenase 1, Leukotriene-B(4) omega-hydroxylase 1,, CYP4F2 (HGNC:2645)
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-CYP4F2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsCYP4F2 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CYP4F2 (HGNC:2645)
Function Omega-hydroxylase that oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids and xenobiotics. Plays a key role in vitamin K catabolism by mediating omega-hydroxylation of vitamin K1 (phylloquinone), and menaquinone-4 (MK-4), a form of vitamin K2. Hydroxylation of phylloquinone and MK-4 probably regulates blood coagulation (PubMed:19297519, PubMed:24138531). Also shows arachidonic acid omega-hydroxylase activity in kidney, by mediating conversion of arachidonic acid to 20-hydroxyeicosatetraenoic acid (20-HETE), possibly influencing blood pressure control (PubMed:10660572, PubMed:17341693, PubMed:18574070). Also acts as a leukotriene-B(4) omega-hydroxylase by mediating conversion of leukotriene-B(4) (LTB4) to its omega-hydroxylated metabolite 20-hydroxyleukotriene- B(4) (20-OH LTB4) (PubMed:8026587, PubMed:9799565).
Cellular Location Microsome membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein
Tissue Location Liver. Also present in kidney: specifically expressed in the S2 and S3 segments of proximal tubules in cortex and outer medulla (PubMed:10660572).
Research Areas
Citations (0)

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Kikuta Y.,et al.FEBS Lett. 348:70-74(1994).
Kikuta Y.,et al.DNA Cell Biol. 18:723-730(1999).
Chen L.,et al.Submitted (JUL-2000) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Grimwood J.,et al.Nature 428:529-535(2004).

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$ 293.00
Cat# AI15007
(40 western blots)
Availability: 2-3 days
Bulk Size
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