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RAP2A antibody - N-terminal region

Rabbit Polyclonal Antibody

  • WB - RAP2A antibody - N-terminal region AI15052

    Target Name:RAP2A
    Sample Tissue:721_B
    Antibody Dilution: 1.0μg/mlRAP2A is strongly supported by BioGPS gene expression data to be expressed in Human 721_B cells
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P10114
Other Accession NM_021033, NP_066361
Reactivity Human, Mouse, Rat, Rabbit, Pig, Sheep, Horse, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Pig, Chicken, Sheep, Horse, Bovine, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 20kDa
Additional Information
Gene ID 5911
Alias Symbol K-REV, KREV, RAP2, RbBP-30
Other Names Ras-related protein Rap-2a, RbBP-30, RAP2A
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-RAP2A antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsRAP2A antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RAP2A
Function Small GTP-binding protein which cycles between a GDP- bound inactive and a GTP-bound active form. In its active form interacts with and regulates several effectors including MAP4K4, MINK1 and TNIK. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it is part of several signaling cascades and may regulate cytoskeletal rearrangements, cell migration, cell adhesion and cell spreading.
Cellular Location Recycling endosome membrane; Lipid-anchor; Cytoplasmic side. Midbody. Note=May also localize to the Golgi (PubMed:7962206) and the gelatinase-containing granules of neutrophils (PubMed:8391995). Colocalizes with RASGEF1B to midbody at telophase (PubMed:23894443).
Research Areas
Citations (0)

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Pizon V.,et al.Oncogene 3:201-204(1988).
Fan Z.S.,et al.Submitted (NOV-1999) to the EMBL/GenBank/DDBJ databases.
Puhl H.L. III,et al.Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Dunham A.,et al.Nature 428:522-528(2004).

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$ 293.00
Cat# AI15052
(40 western blots)
Availability: 2-3 days
Bulk Size
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