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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   RILP antibody - C-terminal region   

RILP antibody - C-terminal region

Rabbit Polyclonal Antibody

     
  • WB - RILP antibody - C-terminal region AI15068

    WB Suggested Anti-RILP Antibody Titration: 1.0 μg/ml
    Positive Control: NCI-H226 Whole Cell
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q96NA2
Other Accession NM_031430, NP_113618
Reactivity Human
Predicted Human
Host Rabbit
Clonality Polyclonal
Calculated MW 44kDa
Additional Information
Gene ID 83547
Alias Symbol FLJ31193, PP10141
Other Names Rab-interacting lysosomal protein, RILP
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-RILP antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsRILP antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RILP
Function Rab effector playing a role in late endocytic transport to degradative compartments. Involved in the regulation of lysosomal morphology and distribution. Induces recruitment of dynein-dynactin motor complexes to Rab7A-containing late endosome and lysosome compartments. Promotes centripetal migration of phagosomes and the fusion of phagosomes with the late endosomes and lysosomes.
Cellular Location Late endosome membrane Lysosome membrane Cytoplasmic vesicle, phagosome membrane. Note=Associated with late endosomal, lysosomal and phagosomal membranes. The interaction with RAB7A is necessary for its recruitment to phagosomes
Tissue Location Ubiquitous. Strongly expressed in fetal heart, heart, stomach, spleen, adrenal gland, thyroid gland, salivary gland, fetal liver, liver and lung. Poorly expressed in brain
Research Areas
Citations (0)

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References

Cantalupo G.,et al.EMBO J. 20:683-693(2001).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Wan D.,et al.Proc. Natl. Acad. Sci. U.S.A. 101:15724-15729(2004).
Frigimelica E.,et al.Submitted (JUL-2000) to the EMBL/GenBank/DDBJ databases.
Bucci C.,et al.Biochem. Biophys. Res. Commun. 286:815-819(2001).

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$ 293.00
Cat# AI15068
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