|Other Accession||NM_007269, NP_009200|
|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Dog|
|Predicted||Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Dog|
|Alias Symbol||MUNC18-3, MUNC18C, PSP, UNC-18C|
|Other Names||Syntaxin-binding protein 3, Platelet Sec1 protein, PSP, Protein unc-18 homolog 3, Unc18-3, Protein unc-18 homolog C, Unc-18C, STXBP3|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-STXBP3 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||STXBP3 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Together with STX4 and VAMP2, may play a role in insulin-dependent movement of GLUT4 and in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes.|
|Cellular Location||Cytoplasm, cytosol. Cell membrane. Note=In platelets, predominantly cytosolic. Low amounts membrane-associated|
|Tissue Location||Megakaryocytes and platelets.|
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Provided below are standard protocols that you may find useful for product applications.
Gengyo-Ando K.,et al.J. Neurosci. 16:6695-6702(1996).
Reed G.L.,et al.Blood 93:2617-2626(1999).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Suzuki Y.,et al.Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
Gregory S.G.,et al.Nature 441:315-321(2006).
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