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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   RFK Antibody - N-terminal region   

RFK Antibody - N-terminal region

Rabbit Polyclonal Antibody

  • WB - RFK Antibody - N-terminal region AI15137

    WB Suggested Anti-RFK Antibody Titration: 1.0 μg/ml
    Positive Control: HepG2 Whole Cell
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q969G6
Other Accession NM_018339, NP_060809
Reactivity Human, Mouse, Rat, Rabbit, Pig, Horse, Yeast, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Rabbit, Pig, Horse, Yeast, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 17kDa
Additional Information
Gene ID 55312
Alias Symbol FLJ11149, RIFK, RP11-422N19.2
Other Names Riboflavin kinase,, ATP:riboflavin 5'-phosphotransferase, Flavokinase, RFK
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-RFK antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsRFK Antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RFK
Function Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin-mononucleotide (FMN), hence rate-limiting enzyme in the synthesis of FAD. Essential for TNF-induced reactive oxygen species (ROS) production. Through its interaction with both TNFRSF1A and CYBA, physically and functionally couples TNFRSF1A to NADPH oxidase. TNF-activation of RFK may enhance the incorporation of FAD in NADPH oxidase, a critical step for the assembly and activation of NADPH oxidase.
Cellular Location Cytoplasm.
Tissue Location Detected in brain, placenta and urinary bladder
Research Areas
Citations (0)

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Ota T.,et al.Nat. Genet. 36:40-45(2004).
Humphray S.J.,et al.Nature 429:369-374(2004).
Yazdanpanah B.,et al.Nature 460:1159-1163(2009).
Burkard T.R.,et al.BMC Syst. Biol. 5:17-17(2011).
Karthikeyan S.,et al.Structure 11:265-273(2003).

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$ 293.00
Cat# AI15137
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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