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TXNRD3 Antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q86VQ6 |
| Other Accession | NM_052883, NP_443115 |
| Reactivity | Human, Mouse, Rabbit |
| Predicted | Human, Mouse, Rabbit |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 70kDa |
| Gene ID | 114112 |
|---|---|
| Alias Symbol | TGR, TR2, TRXR3 |
| Other Names | Thioredoxin reductase 3, 1.8.1.9, Thioredoxin and glutathione reductase, Thioredoxin reductase TR2, TXNRD3 {ECO:0000312|EMBL:AAH50032.1} |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-TXNRD3 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | TXNRD3 Antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TXNRD3 {ECO:0000312|EMBL:AAH50032.1} |
|---|---|
| Function | Displays thioredoxin reductase, glutaredoxin and glutathione reductase activities. Catalyzes disulfide bond isomerization. Promotes disulfide bond formation between GPX4 and various sperm proteins and may play a role in sperm maturation by promoting formation of sperm structural components (By similarity). |
| Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:Q99MD6}. Nucleus {ECO:0000250|UniProtKB:Q99MD6}. Microsome {ECO:0000250|UniProtKB:Q99MD6}. Endoplasmic reticulum Note=Detected in cytoplasm and nucleus in late spermatids {ECO:0000250|UniProtKB:Q99MD6} |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
References
Muzny D.M.,et al.Nature 440:1194-1198(2006).
Sun Q.-A.,et al.J. Biol. Chem. 274:24522-24530(1999).
Miranda-Vizuete A.,et al.Submitted (MAR-1999) to the EMBL/GenBank/DDBJ databases.
Dephoure N.,et al.Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Gerashchenko M.V.,et al.J. Biol. Chem. 285:4595-4602(2010).
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