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RQCD1 Antibody - middle region

Rabbit Polyclonal Antibody

  • WB - RQCD1 Antibody - middle region AI15317

    Host: Rabbit
    Target Name: RQCD1
    Sample Tissue: 721_B Whole cell lysate
    Antibody Dilution: 1.0μg/mlRQCD1 is strongly supported by BioGPS gene expression data to be expressed in Human 721_B cells
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q92600
Other Accession NM_005444, NP_005435
Reactivity Human, Mouse, Rat, Rabbit, Pig, Goat, Horse, Yeast, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Rabbit, Pig, Horse, Yeast, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 34kDa
Additional Information
Gene ID 9125
Alias Symbol CNOT9, CT129, RCD1, RCD1+
Other Names Cell differentiation protein RCD1 homolog, Rcd-1, CCR4-NOT transcription complex subunit 9, RQCD1, CNOT9, RCD1
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-RQCD1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsRQCD1 Antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RQCD1
Synonyms CNOT9, RCD1
Function Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Involved in down-regulation of MYB- and JUN-dependent transcription. May play a role in cell differentiation (By similarity). Can bind oligonucleotides, such as poly-G, poly-C or poly-T (in vitro), but the physiological relevance of this is not certain. Does not bind poly-A. Enhances ligand-dependent transcriptional activity of nuclear hormone receptors, including RARA, expect ESR1-mediated transcription that is not only slightly increased, if at all.
Cellular Location Nucleus. Cytoplasm, P-body. Note=NANOS2 promotes its localization to P-body
Tissue Location Detected in spleen, thymus, prostate, testis, ovary and intestine.
Citations (0)

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Okazaki N.,et al.Mol. Cell. Biol. 18:887-895(1998).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 434:724-731(2005).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Bienvenut W.V.,et al.Submitted (OCT-2009) to UniProtKB.

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$ 293.00
Cat# AI15317
(40 western blots)
Availability: 2-3 days
Bulk Size
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