|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Goat, Sheep, Horse, Bovine, Dog|
|Predicted||Human, Mouse, Rat, Rabbit, Pig, Goat, Sheep, Horse, Bovine, Dog|
|Other Names||Sperm acrosome membrane-associated protein 3, Lysozyme-like protein 3, Sperm lysozyme-like protein 1, mSLLP1, Sperm acrosome membrane-associated protein 3, membrane form, Sperm acrosome membrane-associated protein 3, processed form, Spaca3, Lyc3, Lyzl3, Sllp1|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-Spaca3 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||Spaca3 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||Lyc3, Lyzl3, Sllp1|
|Function||Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. It could be a potential receptor for the egg oligosaccharide residue N-acetylglucosamine, which is present in the extracellular matrix over the egg plasma membrane. The processed form has no detectable bacteriolytic activity in vitro (By similarity).|
|Cellular Location||Cytoplasmic vesicle, secretory vesicle, acrosome membrane; Single-pass type II membrane protein. Note=Anterior acrosome in non-capacitated spermatozoa and retained in the equatorial segment and in the luminal face of both the inner and outer acrosomal membranes following capacitation and the acrosome reaction|
|Tissue Location||The processed form is expressed in sperm (at protein level). Expressed strongly in testis and epididymis and weakly in pancreas.|
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Provided below are standard protocols that you may find useful for product applications.
Zhang K.,et al.Biol. Reprod. 73:1064-1071(2005).
Carninci P.,et al.Science 309:1559-1563(2005).
Church D.M.,et al.PLoS Biol. 7:E1000112-E1000112(2009).
Herrero M.B.,et al.Dev. Biol. 284:126-142(2005).
Sachdev M.,et al.Dev. Biol. 363:40-51(2012).
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