|Other Accession||NM_003249, NP_003240|
|Alias Symbol||EP24.15, MEPD_HUMAN, MP78, TOP|
|Other Names||Thimet oligopeptidase, 220.127.116.11, Endopeptidase 24.15, MP78, THOP1|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-THOP1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||THOP1 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in the metabolism of neuropeptides under 20 amino acid residues long. Involved in cytoplasmic peptide degradation. Able to degrade the beta-amyloid precursor protein and generate amyloidogenic fragments.|
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Provided below are standard protocols that you may find useful for product applications.
Thompson A.,et al.Biochem. Biophys. Res. Commun. 213:66-73(1995).
Taylor G.R.,et al.Submitted (DEC-1995) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Grimwood J.,et al.Nature 428:529-535(2004).
Papastoitsis G.,et al.Biochemistry 33:192-199(1994).
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