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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   CCDC99 Antibody - C-terminal region   

CCDC99 Antibody - C-terminal region

Rabbit Polyclonal Antibody

  • WB - CCDC99 Antibody - C-terminal region AI15481

    Host: Rabbit
    Target Name: CCDC99
    Sample Tissue: Hela Whole cell lysate
    Antibody Dilution: 1.0μg/mlSPDL1 is supported by BioGPS gene expression data to be expressed in HeLa
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q96EA4
Other Accession NM_017785, NP_060255
Reactivity Human, Rat, Rabbit, Pig, Horse, Bovine, Dog
Predicted Human, Rat, Rabbit, Pig, Horse, Bovine, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 67kDa
Additional Information
Gene ID 54908
Alias Symbol FLJ20364, FLJ40690, CCDC99
Other Names Protein Spindly {ECO:0000255|HAMAP-Rule:MF_03041}, hSpindly, Arsenite-related gene 1 protein, Coiled-coil domain-containing protein 99 {ECO:0000255|HAMAP-Rule:MF_03041}, Rhabdomyosarcoma antigen MU-RMS-40.4A, Spindle apparatus coiled-coil domain-containing protein 1 {ECO:0000255|HAMAP-Rule:MF_03041}, SPDL1 {ECO:0000255|HAMAP-Rule:MF_03041}
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-CCDC99 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsCCDC99 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SPDL1 {ECO:0000255|HAMAP-Rule:MF_03041}
Function Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment.
Cellular Location Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Chromosome, centromere, kinetochore. Nucleus. Cytoplasm, cytoskeleton, spindle pole Note=Localizes to the nucleus in interphase and to the kinetochore in early prometaphase. Relocalizes to the mitotic spindle pole before metaphase and is subsequently lost from the spindle poles after chromosome congression is completed. Removal of this protein from the kinetochore requires the dynein/dynactin complex
Research Areas
Citations (0)

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Gu Y.Q.,et al.Submitted (MAY-2000) to the EMBL/GenBank/DDBJ databases.
Behrends U.,et al.Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Schmutz J.,et al.Nature 431:268-274(2004).
Griffis E.R.,et al.J. Cell Biol. 177:1005-1015(2007).

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$ 293.00
Cat# AI15481
(40 western blots)
Availability: 2-3 days
Bulk Size
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