C6orf106 Antibody - C-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | Q9H6K1 |
Other Accession | NM_024294, NP_077270 |
Reactivity | Human, Rat, Rabbit, Horse, Guinea Pig, Dog |
Predicted | Human, Rat, Rabbit, Pig, Horse, Guinea Pig, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 32kDa |
Gene ID | 64771 |
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Alias Symbol | FP852, dJ391O22.4 |
Other Names | Uncharacterized protein C6orf106, C6orf106 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-C6orf106 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | C6orf106 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ILRUN (HGNC:21215) |
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Function | Negative regulator of innate antiviral response. Blocks IRF3- dependent cytokine production such as IFNA, IFNB and TNF (PubMed:29802199). Interacts with IRF3 and inhibits IRF3 recruitment to type I IFN promoter sequences while also reducing nuclear levels of the coactivators EP300 and CREBBP (PubMed:29802199). |
Cellular Location | Cytoplasm. Nucleus |
Tissue Location | Expressed in lung (at protein level). |
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Provided below are standard protocols that you may find useful for product applications.
References
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mungall A.J.,et al.Nature 425:805-811(2003).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Dephoure N.,et al.Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Gauci S.,et al.Anal. Chem. 81:4493-4501(2009).
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