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C11orf94 Antibody - middle region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | C9JXX5 |
| Other Accession | NM_001080446, NP_001073915 |
| Reactivity | Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Dog |
| Predicted | Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 10kDa |
| Gene ID | 143678 |
|---|---|
| Other Names | Uncharacterized protein C11orf94, C11orf94 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-C11orf94 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | C11orf94 Antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | FREY1 (HGNC:37213) |
|---|---|
| Synonyms | C11orf94, FREY |
| Function | Key regulator for male fertility expressed transiently in round spermatids where it recruits IZUMO1 at the endoplasmic reticulum (ER) membrane and coordinates the oolemmal binding multimeric complex (IZUMO1 complex) assembly. Upon complete assembly of the IZUMO1 complex, its ER retention is released, facilitating IZUMO1 complex export to the acrosome. Through the interaction with SPPL2C, inhibits its intramembrane protease activity directly accessing the catalytic center of an I-CLiP. |
| Cellular Location | Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q8CF31}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:Q8CF31} |
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Provided below are standard protocols that you may find useful for product applications.
References
Taylor T.D.,et al.Nature 440:497-500(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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