PPP1R35 Antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB |
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Primary Accession | Q8TAP8 |
Other Accession | NM_145030, NP_659467 |
Reactivity | Human, Rabbit |
Predicted | Human, Rabbit |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 27kDa |
Gene ID | 221908 |
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Alias Symbol | C7orf47 |
Other Names | Protein phosphatase 1 regulatory subunit 35, PPP1R35, C7orf47 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-PPP1R35 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | PPP1R35 Antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | PPP1R35 (HGNC:28320) |
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Function | During centriole duplication, plays a role in the centriole elongation by promoting the recruitment of the microtubule-binding elongation machinery through its interaction with RTTN, leading to the centriole to centrosome conversion (PubMed:30168418, PubMed:30230954). In addition, may play a role in the primary cilia assembly (By similarity). |
Cellular Location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole Note=Recruited to the nascent daughter centriole early in the duplication cycle and localizes to the proximal centriolar lumen just above the cartwheel (PubMed:30168418, PubMed:30230954). Co-localizes with RTTN at the centriole (PubMed:30168418) |

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