|Other Accession||NM_021930, NP_068749|
|Reactivity||Human, Rat, Horse, Guinea Pig|
|Predicted||Human, Rat, Pig, Horse, Guinea Pig|
|Other Names||RAD50-interacting protein 1, RAD50 interactor 1, HsRINT-1, RINT-1, RINT1|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 &mu, l of distilled water. Final Anti-RINT1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||RINT1 Antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in regulation of membrane traffic between the Golgi and the endoplasmic reticulum (ER); the function is proposed to depend on its association in the NRZ complex which is believed to play a role in SNARE assembly at the ER. May play a role in cell cycle checkpoint control (PubMed:11096100). Essential for telomere length control (PubMed:16600870).|
|Cellular Location||Cytoplasm. Endoplasmic reticulum membrane; Peripheral membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
Involved in regulation of membrane traffic between the Golgi and the endoplasmic reticulum. May play a role in cell cycle checkpoint control. Essential for telomere length control.
Xiao J.,et al.J. Biol. Chem. 276:6105-6111(2001).
Hillier L.W.,et al.Nature 424:157-164(2003).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hirose H.,et al.EMBO J. 23:1267-1278(2004).
Nakajima K.,et al.EMBO J. 23:3216-3226(2004).
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