|Other Accession||NM_021930, NP_068749|
|Reactivity||Human, Rat, Horse, Guinea Pig|
|Predicted||Human, Rat, Pig, Horse, Guinea Pig|
|Other Names||RAD50-interacting protein 1, RAD50 interactor 1, HsRINT-1, RINT-1, RINT1|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 &mu, l of distilled water. Final Anti-RINT1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||RINT1 Antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in regulation of membrane traffic between the Golgi and the endoplasmic reticulum (ER); the function is proposed to depend on its association in the NRZ complex which is believed to play a role in SNARE assembly at the ER. May play a role in cell cycle checkpoint control (PubMed:11096100). Essential for telomere length control (PubMed:16600870).|
|Cellular Location||Cytoplasm. Endoplasmic reticulum membrane; Peripheral membrane protein|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Involved in regulation of membrane traffic between the Golgi and the endoplasmic reticulum. May play a role in cell cycle checkpoint control. Essential for telomere length control.
Xiao J.,et al.J. Biol. Chem. 276:6105-6111(2001).
Hillier L.W.,et al.Nature 424:157-164(2003).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hirose H.,et al.EMBO J. 23:1267-1278(2004).
Nakajima K.,et al.EMBO J. 23:3216-3226(2004).
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