|Other Names||cAMP-specific 3', 5'-cyclic phosphodiesterase 7B, 220.127.116.11, PDE7B|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 &mu, l of distilled water. Final Anti-PDE7B antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||PDE7B Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in the control of cAMP-mediated neural activity and cAMP metabolism in the brain.|
|Tissue Location||Highly expressed in brain. Also expressed in heart, liver, skeletal muscle and pancreas|
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Provided below are standard protocols that you may find useful for product applications.
Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in the control of cAMP-mediated neural activity and cAMP metabolism in the brain.
Sasaki T.,et al.Biochem. Biophys. Res. Commun. 271:575-583(2000).
Gardner C.E.,et al.Biochem. Biophys. Res. Commun. 272:186-192(2000).
Mungall A.J.,et al.Nature 425:805-811(2003).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Mayya V.,et al.Sci. Signal. 2:RA46-RA46(2009).
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