|Other Accession||NM_003617, NP_003608|
|Reactivity||Human, Mouse, Rat, Pig, Bovine, Guinea Pig, Dog|
|Predicted||Human, Mouse, Rat, Pig, Bovine, Guinea Pig, Dog|
|Alias Symbol||MST092, MST106, MST129, MSTP032, MSTP092, MSTP106, MSTP129|
|Other Names||Regulator of G-protein signaling 5, RGS5, RGS5|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-RGS5 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||RGS5 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i)-alpha and G(o)-alpha, but not to G(s)-alpha (By similarity).|
|Cellular Location||Isoform 1: Cytoplasm. Membrane|
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Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i)-alpha and G(o)-alpha, but not to G(s)-alpha (By similarity).
Chatterjee T.K.,et al.Submitted (OCT-1997) to the EMBL/GenBank/DDBJ databases.
Seki N.,et al.J. Hum. Genet. 43:202-205(1998).
Cismowski M.J.,et al.Nat. Biotechnol. 17:878-883(1999).
Liang Y.,et al.FEBS J. 272:791-799(2005).
Puhl H.L. III,et al.Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
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