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MAX antibody - N-terminal region

Rabbit Polyclonal Antibody

     
  • WB - MAX antibody - N-terminal region AI16265

    WB Suggested Anti-MAX Antibody Titration: 0.2-1 μg/ml
    ELISA Titer: 1:312500
    Positive Control: COLO205 cell lysate
    There is BioGPS gene expression data showing that MAX is expressed in COLO205
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession P61244
Other Accession NM_145112, NP_660087
Reactivity Human, Mouse, Rat, Dog
Predicted Human, Mouse, Rat, Chicken, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 17kDa
Additional Information
Gene ID 4149
Alias Symbol MGC10775, MGC11225, MGC18164, MGC34679, MGC36767, orf1, bHLHd4, bHLHd5, bHLHd6, bHLHd7, bHLHd8
Other Names Protein max, Class D basic helix-loop-helix protein 4, bHLHd4, Myc-associated factor X, MAX, BHLHD4
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-MAX antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsMAX antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MAX
Synonyms BHLHD4
Function Transcription regulator. Forms a sequence-specific DNA- binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'. The MYC:MAX complex is a transcriptional activator, whereas the MAD:MAX complex is a repressor. May repress transcription via the recruitment of a chromatin remodeling complex containing H3 'Lys-9' histone methyltransferase activity.
Cellular Location Nucleus. Cell projection, dendrite
Tissue Location High levels found in the brain, heart and lung while lower levels are seen in the liver, kidney and skeletal muscle
Citations (0)

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Background

Transcription regulator. Forms a sequence-specific DNA- binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'. The MYC:MAX complex is a transcriptional activator, whereas the MAD:MAX complex is a repressor. May repress transcription via the recruitment of a chromatin remodeling complex containing H3 'Lys-9' histone methyltransferase activity.

References

Blackwood E.M.,et al.Science 251:1211-1217(1991).
Vaestrik I.,et al.Oncogene 8:503-507(1993).
Maekelae T.P.,et al.Science 256:373-377(1992).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Heilig R.,et al.Nature 421:601-607(2003).

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$ 293.00
Cat# AI16265
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