|Dilution||IHC-P (4 µg/ml)|
|Other Names||Endothelin B receptor, ET-B, ET-BR, Endothelin receptor non-selective type, EDNRB, ETRB|
|Target/Specificity||Human EDNRB. BLAST analysis of the peptide immunogen showed no homology with other human proteins.|
|Reconstitution & Storage||Long term: -70°C; Short term: +4°C|
|Precautions||EDNRB / Endothelin B Receptor Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Non-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.|
|Cellular Location||Cell membrane; Multi-pass membrane protein. Note=internalized after activation by endothelins.|
|Tissue Location||Expressed in placental stem villi vessels, but not in cultured placental villi smooth muscle cells|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Non-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
Nakamuta M.,et al.Biochem. Biophys. Res. Commun. 177:34-39(1991).
Ogawa Y.,et al.Biochem. Biophys. Res. Commun. 178:248-255(1991).
Sakamoto A.,et al.Biochem. Biophys. Res. Commun. 178:656-663(1991).
Haendler B.,et al.J. Cardiovasc. Pharmacol. 20:S1-S4(1992).
Arai H.,et al.Jpn. Circ. J. 56:1303-1307(1992).
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