|Application ||IHC-P, E|
|Dilution||IHC-P (10 µg/ml)|
|Other Names||Prosaposin receptor GPR37L1, Endothelin B receptor-like protein 2, ETBR-LP-2, G-protein coupled receptor 37-like 1, GPR37L1, ETBRLP2|
|Target/Specificity||Human GPR37L1. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except FOXR1 (50%).|
|Reconstitution & Storage||Long term: -70°C; Short term: +4°C|
|Precautions||GPR37L1 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for the neuroprotective and glioprotective factor prosaposin. Ligand binding induces endocytosis, followed by an ERK phosphorylation cascade.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Expressed in the central nervous system.|
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Provided below are standard protocols that you may find useful for product applications.
Receptor for the neuroprotective and glioprotective factor prosaposin. Ligand binding induces endocytosis, followed by an ERK phosphorylation cascade.
Valdenaire O.,et al.FEBS Lett. 424:193-196(1998).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Suzuki Y.,et al.Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
Gregory S.G.,et al.Nature 441:315-321(2006).
Halim A.,et al.J. Proteome Res. 12:573-584(2013).
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