|Reactivity||Human, Monkey, Guinea Pig|
|Dilution||IHC-P (10 µg/ml)|
|Other Names||Brain-specific angiogenesis inhibitor 2, BAI2|
|Target/Specificity||Human BAI2. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except PNMAL1 (53%).|
|Reconstitution & Storage||Long term: -70°C; Short term: +4°C|
|Precautions||ADGRB2 / BAI2 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Orphan receptor involved in cell adhesion and probably in cell-cell interactions. Activates NFAT signaling pathway probably via a G-protein dependent pathway (PubMed:20367554). Might be involved in angiogenesis inhibition (By similarity).|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Strongly expressed in brain. Also detected in heart, thymus, skeletal muscle, and different cell lines|
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Might be involved in angiogenesis inhibition.
Shiratsuchi T.,et al.Cytogenet. Cell Genet. 79:103-108(1997).
Suwa M.,et al.Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases.
Gregory S.G.,et al.Nature 441:315-321(2006).
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