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F2RL3 / PAR4 Antibody (Extracellular Domain)

Rabbit Polyclonal Antibody

     
  • IHC - F2RL3 / PAR4 Antibody (Extracellular Domain) ALS10331
    Anti-F2RL3 / PAR4 antibody ALS10331 IHC of human bone marrow.
  • IHC - F2RL3 / PAR4 Antibody (Extracellular Domain) ALS10331
    Anti-F2RL3 / PAR4 antibody IHC of human Ovary, Carcinoma.
  • IHC - F2RL3 / PAR4 Antibody (Extracellular Domain) ALS10331
    Anti-F2RL3 / PAR4 antibody IHC of human Lymph Node, Hodgkins Lymphoma.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P
Primary Accession Q96RI0
Reactivity Human, Monkey
Host Rabbit
Clonality Polyclonal
Calculated MW 41kDa
Dilution IHC-P (2-5 µg/ml)
Additional Information
Gene ID 9002
Other Names Proteinase-activated receptor 4, PAR-4, Coagulation factor II receptor-like 3, Thrombin receptor-like 3, F2RL3, PAR4
Target/Specificity Human F2RL3 / PAR4. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Reconstitution & Storage Long term: -70°C; Short term: +4°C
PrecautionsF2RL3 / PAR4 Antibody (Extracellular Domain) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name F2RL3
Synonyms PAR4
Function Receptor for activated thrombin or trypsin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation.
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Widely expressed, with highest levels in lung, pancreas, thyroid, testis and small intestine. Not expressed in brain, kidney, spinal cord and peripheral blood leukocytes. Also detected in platelets
Volume 50 µl
Research Areas
Citations (0)

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Background

Receptor for activated thrombin or trypsin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation.

References

Kahn M.L.,et al.J. Biol. Chem. 273:23290-23296(1998).
Kahn M.L.,et al.Nature 394:690-694(1998).
Xu W.-F.,et al.Proc. Natl. Acad. Sci. U.S.A. 95:6642-6646(1998).
King M.M.,et al.Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.
Kahn M.L.,et al.J. Clin. Invest. 103:879-887(1999).

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$ 395.00
Cat# ALS10331
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