|Dilution||IHC-P (21-42 µg/ml)|
|Other Names||EGF-like module-containing mucin-like hormone receptor-like 3, EGF-like module receptor 3, EGF-like module-containing mucin-like hormone receptor-like 3 subunit alpha, EGF-like module-containing mucin-like hormone receptor-like 3 subunit beta, EMR3|
|Target/Specificity||Human EMR3. BLAST analysis of the peptide immunogen showed no homology with other human proteins.|
|Reconstitution & Storage||Long term: -70°C; Short term: +4°C|
|Precautions||ADGRE3 / EMR3 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Orphan receptor that may play a role myeloid-myeloid interactions during immune and inflammatory responses. A ligand for the soluble form of this receptor is present at the surface of monocytes-derived macrophages and activated neutrophils.|
|Cellular Location||Cell membrane; Multi-pass membrane protein|
|Tissue Location||Displays a predominantly leukocyte-restricted expression, with highest levels in neutrophils, monocytes and macrophages.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Receptor probably involved in myeloid interactions during immune and inflammatory responses. A ligand for the soluble form of this receptor is present at the surface of momocytes- derived macrophages and activated neutrophils.
Stacey M.,et al.J. Biol. Chem. 276:18863-18870(2001).
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Grimwood J.,et al.Nature 428:529-535(2004).
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