|Dilution||IHC-P (17-23 µg/ml)|
|Other Names||Prokineticin receptor 2, PK-R2, G-protein coupled receptor 73-like 1, GPR73b, GPRg2, PROKR2, GPR73L1, PKR2|
|Target/Specificity||Human PROKR2. BLAST analysis of the peptide immunogen showed no homology with other human proteins.|
|Reconstitution & Storage||Long term: -70°C; Short term: +4°C|
|Precautions||PROKR2/Prokineticin Receptor 2 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for prokineticin 2. Exclusively coupled to the G(q) subclass of heteromeric G proteins. Activation leads to mobilization of calcium, stimulation of phosphoinositide turnover and activation of p44/p42 mitogen-activated protein kinase.|
|Cellular Location||Cell membrane; Multi-pass membrane protein|
|Tissue Location||Expressed in the ileocecum, thyroid gland, pituitary gland, salivary gland, adrenal gland, testis, ovary and brain|
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Provided below are standard protocols that you may find useful for product applications.
Receptor for prokineticin 2. Exclusively coupled to the G(q) subclass of heteromeric G proteins. Activation leads to mobilization of calcium, stimulation of phosphoinositide turnover and activation of p44/p42 mitogen-activated protein kinase.
Lin D.C.-H.,et al.J. Biol. Chem. 277:19276-19280(2002).
Soga T.,et al.Biochim. Biophys. Acta 1579:173-179(2002).
Martin A.L.,et al.Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
Deloukas P.,et al.Nature 414:865-871(2001).
Marsango S.,et al.Cell. Mol. Life Sci. 68:2919-2929(2011).
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