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P2RY1 / P2Y1 Antibody (C-Terminus)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, ICC |
|---|---|
| Primary Accession | P47900 |
| Reactivity | Human, Mouse, Rabbit, Hamster, Monkey, Bovine, Guinea Pig, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 42kDa |
| Dilution | IHC-P (2-5 µg/ml) |
| Gene ID | 5028 |
|---|---|
| Other Names | P2Y purinoceptor 1, P2Y1, ATP receptor, Purinergic receptor, P2RY1 |
| Target/Specificity | Human P2RY1 / P2Y1. BLAST analysis of the peptide immunogen showed no homology with other human proteins. |
| Reconstitution & Storage | Long term: -70°C; Short term: +4°C |
| Precautions | P2RY1 / P2Y1 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | P2RY1 |
|---|---|
| Function | Receptor for extracellular adenine nucleotides such as ADP (PubMed:9442040, PubMed:9038354, PubMed:25822790). In platelets, binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and ultimately platelet aggregation (PubMed:9442040). |
| Cellular Location | Cell membrane; Multi-pass membrane protein |
| Volume | 50 µl |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Receptor for extracellular adenine nucleotides such as ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation.
References
Leon C.,et al.Gene 171:295-297(1996).
Ayyanathan K.,et al.Biochem. Biophys. Res. Commun. 218:783-788(1996).
Janssens R.,et al.Biochem. Biophys. Res. Commun. 221:588-593(1996).
Leon C.,et al.Submitted (JUN-1998) to the EMBL/GenBank/DDBJ databases.
Puhl H.L. III,et al.Submitted (JUL-2002) to the EMBL/GenBank/DDBJ databases.
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