|Dilution||IHC-P (6 µg/ml)|
|Other Names||N-arachidonyl glycine receptor, NAGly receptor, G-protein coupled receptor 18, GPR18, GPCRW|
|Target/Specificity||Human GPR18. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except GPR174 (44%).|
|Reconstitution & Storage||Long term: -70°C; Short term: +4°C|
|Precautions||GPCRW / GPR18 Antibody (Extracellular Domain) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for N-arachidonyl glycine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. May contribute to regulation of the immune system.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Most abundant in testis and spleen. Highly expressed in CD4 and CD8-positive T-cells as well as CD19-positive B-cells.|
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Provided below are standard protocols that you may find useful for product applications.
Receptor for N-arachidonyl glycine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. May contribute to regulation of the immune system.
Gantz I.,et al.Genomics 42:462-466(1997).
Kohno M.,et al.Biochem. Biophys. Res. Commun. 347:827-832(2006).
Xu X.,et al.Submitted (MAY-2000) to the EMBL/GenBank/DDBJ databases.
Kalnine N.,et al.Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
Dunham A.,et al.Nature 428:522-528(2004).
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