|Dilution||IHC-P (15-30 µg/ml)|
|Other Names||Alpha-2C adrenergic receptor, Alpha-2 adrenergic receptor subtype C4, Alpha-2C adrenoreceptor, Alpha-2C adrenoceptor, Alpha-2CAR, ADRA2C, ADRA2L2, ADRA2RL2|
|Target/Specificity||Human ADRA2C. BLAST analysis of the peptide immunogen showed no homology with other human proteins.|
|Reconstitution & Storage||Long term: -70°C; Short term: +4°C|
|Precautions||ADRA2C Antibody (Extracellular Domain) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
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Provided below are standard protocols that you may find useful for product applications.
Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins.
Regan J.W.,et al.Proc. Natl. Acad. Sci. U.S.A. 85:6301-6305(1988).
Schaak S.,et al.Biochem. J. 328:431-438(1997).
Yano K.,et al.Submitted (OCT-1992) to the EMBL/GenBank/DDBJ databases.
Small K.M.,et al.J. Biol. Chem. 275:23059-23064(2000).
Small K.M.,et al.Proc. Natl. Acad. Sci. U.S.A. 101:13020-13025(2004).
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