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CNR1 / CB1 Antibody (N-Terminus)

Rabbit Polyclonal Antibody

     
  • IHC - CNR1 / CB1 Antibody (N-Terminus) ALS10724
    Anti-CNR1 / CB1 antibody ALS10724 IHC of human brain, neurons and glia.
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P
Primary Accession P21554
Reactivity Human, Mouse, Hamster, Horse, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 53kDa
Dilution IHC-P (10 µg/ml)
Additional Information
Gene ID 1268
Other Names Cannabinoid receptor 1, CB-R, CB1, CANN6, CNR1, CNR
Target/Specificity Human CNR1 / CB1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Reconstitution & Storage Long term: -70°C; Short term: +4°C
PrecautionsCNR1 / CB1 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CNR1
Synonyms CNR
Function Involved in cannabinoid-induced CNS effects. Acts by inhibiting adenylate cyclase. Could be a receptor for anandamide. Inhibits L-type Ca(2+) channel current. Isoform 2 and isoform 3 have altered ligand binding.
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Widely expressed.
Volume 50 µl
Research Areas
Citations (0)

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Background

Involved in cannabinoid-induced CNS effects. Acts by inhibiting adenylate cyclase. Could be a receptor for anandamide. Inhibits L-type Ca(2+) channel current. Isoform 2 and isoform 3 have altered ligand binding.

References

Gerard C.,et al.Nucleic Acids Res. 18:7142-7142(1990).
Gerard C.,et al.Biochem. J. 279:129-134(1991).
Shire D.,et al.J. Biol. Chem. 270:3726-3731(1995).
Ryberg E.,et al.FEBS Lett. 579:259-264(2005).
Kathmann M.,et al.Submitted (NOV-1998) to the EMBL/GenBank/DDBJ databases.

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$ 395.00
Cat# ALS10724
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