|Reactivity||Human, Mouse, Rabbit, Hamster, Monkey, Horse, Bovine, Dog|
|Dilution||IHC-P (5 µg/ml)|
|Other Names||Estrogen-related receptor gamma, ERR gamma-2, Estrogen receptor-related protein 3, Nuclear receptor subfamily 3 group B member 3, ESRRG, ERR3, ERRG2, KIAA0832, NR3B3|
|Target/Specificity||Human ESRRG / ERR3. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except ESRRB (64%).|
|Reconstitution & Storage||Long term: -70°C; Short term: +4°C|
|Precautions||ESRRG / ERR Gamma Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||ERR3, ERRG2, KIAA0832, NR3B3|
|Function||Orphan receptor that acts as transcription activator in the absence of bound ligand. Binds specifically to an estrogen response element and activates reporter genes controlled by estrogen response elements (By similarity). Induces the expression of PERM1 in the skeletal muscle.|
|Tissue Location||Expressed in the heart, kidney, brain, lung, bone marrow, adrenal gland, trachea, spinal cord and thyroid gland.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Orphan receptor that acts as transcription activator in the absence of bound ligand. Binds specifically to an estrogen response element and activates reporter genes controlled by estrogen response elements (By similarity). Induces the expression of PERM1 in the skeletal muscle.
Chen F.,et al.Gene 228:101-109(1999).
Nagase T.,et al.DNA Res. 5:355-364(1998).
Eudy J.D.,et al.Genomics 50:382-384(1998).
Heard D.J.,et al.Mol. Endocrinol. 14:382-392(2000).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.