|Reactivity||Human, Mouse, Rabbit, Hamster, Monkey, Horse, Bovine, Dog|
|Dilution||IHC-P (5 µg/ml)|
|Other Names||Estrogen-related receptor gamma, ERR gamma-2, Estrogen receptor-related protein 3, Nuclear receptor subfamily 3 group B member 3, ESRRG, ERR3, ERRG2, KIAA0832, NR3B3|
|Target/Specificity||Human ESRRG / ERR3. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except ESRRB (64%).|
|Reconstitution & Storage||Long term: -70°C; Short term: +4°C|
|Precautions||ESRRG / ERR Gamma Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||ERR3, ERRG2, KIAA0832, NR3B3|
|Function||Orphan receptor that acts as transcription activator in the absence of bound ligand. Binds specifically to an estrogen response element and activates reporter genes controlled by estrogen response elements (By similarity). Induces the expression of PERM1 in the skeletal muscle.|
|Tissue Location||Expressed in the heart, kidney, brain, lung, bone marrow, adrenal gland, trachea, spinal cord and thyroid gland.|
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Orphan receptor that acts as transcription activator in the absence of bound ligand. Binds specifically to an estrogen response element and activates reporter genes controlled by estrogen response elements (By similarity). Induces the expression of PERM1 in the skeletal muscle.
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Eudy J.D.,et al.Genomics 50:382-384(1998).
Heard D.J.,et al.Mol. Endocrinol. 14:382-392(2000).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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