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CALCRL / CGRP Receptor Antibody (Cytoplasmic Domain)

Rabbit Polyclonal Antibody

     
  • IHC - CALCRL  / CGRP Receptor Antibody (Cytoplasmic Domain) ALS10868
    Anti-CALCRL / CGRP Receptor antibody IHC of human Bone, Osteosarcoma.
  • IHC - CALCRL  / CGRP Receptor Antibody (Cytoplasmic Domain) ALS10868
    Anti-CALCRL antibody ALS10868 IHC of human colon, submucosal plexus and submucosal vessels.
  • IHC - CALCRL  / CGRP Receptor Antibody (Cytoplasmic Domain) ALS10868
    Anti-CALCRL / CGRP Receptor antibody IHC of human Lung, Non-Small Cell Carcinoma.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P
Primary Accession Q16602
Reactivity Human, Rabbit, Hamster, Monkey, Pig, Horse, Xenopus, Bovine, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 53kDa
Dilution IHC-P (34 µg/ml)
Additional Information
Gene ID 10203
Other Names Calcitonin gene-related peptide type 1 receptor, CGRP type 1 receptor, Calcitonin receptor-like receptor, CALCRL, CGRPR
Target/Specificity Human CALCRL. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except CALCR (56%).
Reconstitution & Storage Long term: -70°C; Short term: +4°C
PrecautionsCALCRL / CGRP Receptor Antibody (Cytoplasmic Domain) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CALCRL
Synonyms CGRPR
Function Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP3 (By similarity). Receptor for adrenomedullin together with RAMP2. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Predominantly expressed in the lung and heart.
Volume 50 µl
Research Areas
Citations (0)

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Background

Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP3 (By similarity). Receptor for adrenomedullin together with RAMP2. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

References

Aiyar N.,et al.J. Biol. Chem. 271:11325-11329(1996).
Fluehmann B.,et al.Biochem. Biophys. Res. Commun. 206:341-347(1995).
Kopatz S.A.,et al.Submitted (SEP-2003) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 434:724-731(2005).

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$ 395.00
Cat# ALS10868
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