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ATRN / Attractin Antibody (Internal)

Rabbit Polyclonal Antibody

     
  • IHC - ATRN / Attractin Antibody (Internal) ALS10970
    Anti-ATRN / Attractin antibody ALS10970 IHC of human spleen.
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P
Primary Accession O75882
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 159kDa
Dilution IHC-P (20 µg/ml)
Additional Information
Gene ID 8455
Other Names Attractin, DPPT-L, Mahogany homolog, ATRN, KIAA0548, MGCA
Target/Specificity Human ATRN / Attractin. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except KCTD19 (50%).
Reconstitution & Storage Long term: -70°C; Short term: +4°C
PrecautionsATRN / Attractin Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ATRN
Synonyms KIAA0548, MGCA
Function Involved in the initial immune cell clustering during inflammatory response and may regulate chemotactic activity of chemokines. May play a role in melanocortin signaling pathways that regulate energy homeostasis and hair color. Low-affinity receptor for agouti (By similarity). Has a critical role in normal myelination in the central nervous system (By similarity).
Cellular Location Isoform 1: Cell membrane; Single-pass type I membrane protein Isoform 3: Secreted
Tissue Location Isoform 2 is detected in plasma (at protein level). Expressed and secreted by activated T-lymphocytes Expressed at low to moderate levels in peripheral blood leukocytes, spleen, lymph node, tonsil, bone marrow and fetal liver. At very low levels found in thymus. Isoform 2 is the major isoform in peripheral blood leukocytes
Volume 50 µl
Research Areas
Citations (0)

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Background

Involved in the initial immune cell clustering during inflammatory response and may regulate chemotactic activity of chemokines. May play a role in melanocortin signaling pathways that regulate energy homeostasis and hair color. Low-affinity receptor for agouti (By similarity). Has a critical role in normal myelination in the central nervous system (By similarity).

References

Tang W.,et al.Proc. Natl. Acad. Sci. U.S.A. 97:6025-6030(2000).
Duke-Cohan J.S.,et al.Submitted (NOV-1998) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Deloukas P.,et al.Nature 414:865-871(2001).
Duke-Cohan J.S.,et al.J. Biol. Chem. 270:14107-14114(1995).

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$ 395.00
Cat# ALS10970
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