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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   EMB/ Embigin Antibody (C-Terminus)   

EMB/ Embigin Antibody (C-Terminus)

Rabbit Polyclonal Antibody

     
  • IHC - EMB/ Embigin Antibody (C-Terminus) ALS11022
    Anti-EMB antibody ALS11022 IHC of human placenta.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P
Primary Accession Q6PCB8
Reactivity Human, Monkey
Host Rabbit
Clonality Polyclonal
Calculated MW 37kDa
Dilution IHC-P (10 µg/ml)
Additional Information
Gene ID 133418
Other Names Embigin, EMB
Target/Specificity Human EMB. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except RALGPS1 (53%).
Reconstitution & Storage Long term: -70°C; Short term: +4°C
PrecautionsEMB/ Embigin Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name EMB
Function Plays a role in the outgrowth of motoneurons and in the formation of neuromuscular junctions. Following muscle denervation, promotes nerve terminal sprouting and the formation of additional acetylcholine receptor clusters at synaptic sites without affecting terminal Schwann cell number or morphology. Delays the retraction of terminal sprouts following re-innervation of denervated endplates. May play a role in targeting the monocarboxylate transporters SLC16A1 and SLC16A7 to the cell membrane (By similarity).
Cellular Location Cell membrane {ECO:0000250|UniProtKB:O88775}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:O88775}. Cell junction, synapse {ECO:0000250|UniProtKB:P21995}. Note=Localizes to the neuromuscular junctions. {ECO:0000250|UniProtKB:P21995}
Volume 50 µl
Research Areas
Citations (0)

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Background

Plays a role in the outgrowth of motoneurons and in the formation of neuromuscular junctions. Following muscle denervation, promotes nerve terminal sprouting and the formation of additional acetylcholine receptor clusters at synaptic sites without affecting terminal Schwann cell number or morphology. Delays the retraction of terminal sprouts following re-innervation of denervated endplates. May play a role in targeting the monocarboxylate transporters SLC16A1 and SLC16A7 to the cell membrane (By similarity).

References

Ota T.,et al.Nat. Genet. 36:40-45(2004).
Schmutz J.,et al.Nature 431:268-274(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Wollscheid B.,et al.Nat. Biotechnol. 27:378-386(2009).

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$ 395.00
Cat# ALS11022
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