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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   SLC7A2 Antibody (C-Terminus)   

SLC7A2 Antibody (C-Terminus)

Rabbit Polyclonal Antibody

     
  • IHC - SLC7A2 Antibody (C-Terminus) ALS11088
    Anti-SLC7A2 antibody ALS11088 IHC of human stomach.
  • IHC - SLC7A2 Antibody (C-Terminus) ALS11088
    Anti-SLC7A2 antibody ALS11088 IHC of human pancreas.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P
Primary Accession P52569
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 72kDa
Dilution IHC-P (15 µg/ml)
Additional Information
Gene ID 6542
Other Names Cationic amino acid transporter 2, CAT-2, CAT2, Low affinity cationic amino acid transporter 2, Solute carrier family 7 member 2, SLC7A2, ATRC2, CAT2
Target/Specificity Human SLC7A2. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Reconstitution & Storage Long term: -70°C; Short term: +4°C
PrecautionsSLC7A2 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SLC7A2
Synonyms ATRC2, CAT2
Function Functions as permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine); the affinity for its substrates differs between isoforms created by alternative splicing. Isoform 1 functions as permease that mediates the transport of the cationic amino acids (arginine, lysine and ornithine), and it has much higher affinity for arginine than isoform 2. Isoform 2 functions as low-affinity, high capacity permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine) (PubMed:9174363). May play a role in classical or alternative activation of macrophages via its role in arginine transport.
Cellular Location Cell membrane; Multi-pass membrane protein
Tissue Location Expressed at high levels in the skeletal muscle, placenta and ovary. Expressed at intermediate levels in the liver and pancreas and at low levels in the kidney and heart
Volume 50 µl
Research Areas
Citations (0)

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Background

Functions as permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine); the affinity for its substrates differs between isoforms created by alternative splicing. Isoform 1 functions as permease that mediates the transport of the cationic amino acids (arginine, lysine and ornithine), and it has much higher affinity for arginine than isoform 2. Isoform 2 functions as low-affinity, high capacity permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine) (PubMed:9174363). May play a role in classical or alternative activation of macrophages via its role in arginine transport.

References

Hoshide R.,et al.Genomics 38:174-178(1996).
Closs E.I.,et al.Biochemistry 36:6462-6468(1997).
Nusbaum C.,et al.Nature 439:331-335(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Bechtel S.,et al.BMC Genomics 8:399-399(2007).

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$ 395.00
Cat# ALS11088
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