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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   WNT10B Antibody (Internal)   

WNT10B Antibody (Internal)

Rabbit Polyclonal Antibody

     
  • IHC - WNT10B Antibody (Internal) ALS11137
    Anti-WNT10B antibody ALS11137 IHC of human skin.
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P
Primary Accession O00744
Reactivity Human, Mouse, Rabbit, Monkey, Pig, Horse, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 43kDa
Dilution IHC-P (10-15 µg/ml)
Additional Information
Gene ID 7480
Other Names Protein Wnt-10b, Protein Wnt-12, WNT10B, WNT12
Target/Specificity Human WNT10B. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Reconstitution & Storage Long term: -70°C; Short term: +4°C
PrecautionsWNT10B Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name WNT10B
Synonyms WNT12
Function Member of the Wnt ligand gene family that encodes for secreted proteins, which activate the Wnt signaling cascade. Specifically activates canonical Wnt/beta-catenin signaling and thus triggers beta-catenin/LEF/TCF-mediated transcriptional programs. Involved in signaling networks controlling stemness, pluripotency and cell fate decisions. Acts in the immune system, mammary gland, adipose tissue, bone and skin.
Cellular Location Secreted, extracellular space, extracellular matrix
Tissue Location Detected in most adult tissues. Highest levels were found in heart and skeletal muscle. Low levels are found in brain
Volume 50 µl
Research Areas
Citations (0)

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Background

Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters (By similarity).

References

Hardiman G.,et al.Cytogenet. Cell Genet. 77:278-282(1997).
Saitoh T.,et al.Int. J. Oncol. 19:1187-1192(2001).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Scherer S.E.,et al.Nature 440:346-351(2006).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.

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$ 395.00
Cat# ALS11137
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