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SRPX2 Antibody (C-Terminus)

Rabbit Polyclonal Antibody

     
  • IHC - SRPX2 Antibody (C-Terminus) ALS11193
    Anti-SRPX2 antibody ALS11193 IHC of human brain, cortex.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P
Primary Accession O60687
Reactivity Human, Monkey
Host Rabbit
Clonality Polyclonal
Calculated MW 53kDa
Dilution IHC-P (10 µg/ml)
Additional Information
Gene ID 27286
Other Names Sushi repeat-containing protein SRPX2, Sushi-repeat protein upregulated in leukemia, SRPX2, SRPUL
Target/Specificity Human SRPX2. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Reconstitution & Storage Long term: -70°C; Short term: +4°C
PrecautionsSRPX2 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SRPX2
Synonyms SRPUL
Function Acts as a ligand for the urokinase plasminogen activator surface receptor. Plays a role in angiogenesis by inducing endothelial cell migration and the formation of vascular network (cords). Involved in cellular migration and adhesion. Increases the phosphorylation levels of FAK. Interacts with and increases the mitogenic activity of HGF. Promotes synapse formation. May have a role in the perisylvian region, critical for language and cognitive development.
Cellular Location Secreted. Cytoplasm. Cell surface. Cell junction, synapse
Tissue Location Expressed in neurons of the rolandic area of the brain (at protein level). Highly expressed in the brain, placenta, lung, trachea, uterus, adrenal gland, heart, ovary and placenta. Weakly expressed in the peripheral blood, brain and bone marrow. Expressed in numerous cancer cell lines and in gastrointestinal cancer cells. Higher levels found in colorectal cancers than in normal colonic mucosa
Volume 50 µl
Research Areas
Citations (0)

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Background

Acts as a ligand for the urokinase plasminogen activator surface receptor. Plays a role in angiogenesis by inducing endothelial cell migration and the formation of vascular network (cords). Involved in cellular migration and adhesion. Increases the phosphorylation levels of FAK. Interacts with and increases the mitogenic activity of HGF. Promotes synapse formation. May have a role in the perisylvian region, critical for language and cognitive development.

References

Kurosawa H.,et al.Blood 93:321-332(1999).
Huang C.-H.,et al.Submitted (JUN-2001) to the EMBL/GenBank/DDBJ databases.
Otsuki T.,et al.DNA Res. 12:117-126(2005).
Ross M.T.,et al.Nature 434:325-337(2005).
Roll P.,et al.Hum. Mol. Genet. 15:1195-1207(2006).

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$ 395.00
Cat# ALS11193
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