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>   home   >   Products   >   Primary Antibodies   >   Metabolism   >   NRF1 / NRF-1 Antibody (aa1-534)   

NRF1 / NRF-1 Antibody (aa1-534)

Rabbit Polyclonal Antibody

     
  • IHC - NRF1 / NRF-1 Antibody (aa1-534) ALS11224
    Anti-NRF1 antibody IHC of human testis.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q16656
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Calculated MW 54kDa
Dilution ELISA (1:3000-1:10000), IHC-P (2-5 µg/ml), WB (1:500-1:2000)
Additional Information
Gene ID 4899
Other Names Nuclear respiratory factor 1, NRF-1, Alpha palindromic-binding protein, Alpha-pal, NRF1
Target/Specificity Purified recombinant mouse NRF1 protein corresponding to aa 1-534 of the native protein.
Reconstitution & Storage Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles.
PrecautionsNRF1 / NRF-1 Antibody (aa1-534) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NRF1
Function Transcription factor that activates the expression of the EIF2S1 (EIF2-alpha) gene. Links the transcriptional modulation of key metabolic genes to cellular growth and development. Implicated in the control of nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication.
Cellular Location Nucleus.
Tissue Location Ubiquitously expressed with strongest expression in skeletal muscle
Research Areas
Citations (0)

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Background

Transcription factor that activates the expression of the EIF2S1 (EIF2-alpha) gene. Links the transcriptional modulation of key metabolic genes to cellular growth and development. Implicated in the control of nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication.

References

Virbasius C.A.,et al.Genes Dev. 7:2431-2445(1993).
Efiok B.J.S.,et al.J. Biol. Chem. 269:18921-18930(1994).
Gopalakrishnan L.,et al.J. Biol. Chem. 270:18019-18025(1995).
Yang S.J.,et al.Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).

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$ 395.00
Cat# ALS11224
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