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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   Adiponectin Antibody (C-Terminus)   

Adiponectin Antibody (C-Terminus)

Rabbit Polyclonal Antibody

     
  • IF - Adiponectin Antibody (C-Terminus) ALS11372
    Immunofluorescence of Adiponectin in Rat Brain cells with Adiponectin antibody at 10 ug/ml.
  • WB - Adiponectin Antibody (C-Terminus) ALS11372
    Western blot of adiponectin in HL60 cell lysate with adiponectin antibody at (A) 0.5, (B) 1, and...
  • IHC - Adiponectin Antibody (C-Terminus) ALS11372
    Anti-Adiponectin antibody IHC of human heart.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF
Primary Accession Q15848
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 26kDa
Dilution IHC-P (2.5 µg/ml), WB (1 µg/ml),
Additional Information
Gene ID 9370
Other Names Adiponectin, 30 kDa adipocyte complement-related protein, Adipocyte complement-related 30 kDa protein, ACRP30, Adipocyte, C1q and collagen domain-containing protein, Adipose most abundant gene transcript 1 protein, apM-1, Gelatin-binding protein, ADIPOQ, ACDC, ACRP30, APM1, GBP28
Target/Specificity 15 amino acid peptide from near the carboxy-terminus of human adiponectin
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
PrecautionsAdiponectin Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ADIPOQ
Synonyms ACDC, ACRP30, APM1, GBP28
Function Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.
Cellular Location Secreted.
Tissue Location Synthesized exclusively by adipocytes and secreted into plasma
Research Areas
Citations (0)

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Background

Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.

References

Maeda K.,et al.Biochem. Biophys. Res. Commun. 221:286-289(1996).
Saito K.,et al.Gene 229:67-73(1999).
Schaeffler A.,et al.Biochem. Biophys. Res. Commun. 260:416-425(1999).
Zhang Z.,et al.Protein Sci. 13:2819-2824(2004).
Nakano Y.,et al.J. Biochem. 120:803-812(1996).

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$ 395.00
Cat# ALS11372
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