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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   AVEN / PDCD12 Antibody (C-Terminus)   

AVEN / PDCD12 Antibody (C-Terminus)

Rabbit Polyclonal Antibody

     
  • IF - AVEN / PDCD12 Antibody (C-Terminus) ALS11376
    Immunofluorescence of AVEN in Human Spleen cells with AVEN antibody at 20 ug/ml.
  • WB - AVEN / PDCD12 Antibody (C-Terminus) ALS11376
    Western blot of Aven in Raji cell lysate with Aven antibody at 1 ug/ml in (A) the presence and...
  • IHC - AVEN / PDCD12 Antibody (C-Terminus) ALS11376
    Anti-AVEN antibody IHC of human testis.
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF
Primary Accession Q9NQS1
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 39kDa
Dilution IHC-P (2.5 µg/ml), WB (0.5-1 µg/ml),
Additional Information
Other Names Cell death regulator Aven, AVEN
Target/Specificity 14 amino acid peptide from near the carboxy terminus of human Aven
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
PrecautionsAVEN / PDCD12 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name AVEN
Function Protects against apoptosis mediated by Apaf-1.
Cellular Location Endomembrane system; Peripheral membrane protein. Note=Associated with intracellular membranes
Tissue Location Highly expressed in testis, ovary, thymus, prostate, spleen, small intestine, colon, heart, skeletal muscle, liver, kidney and pancreas EMBL; AF283508; AAF91470.1; -; mRNA EMBL; BC010488; AAH10488.1; -; mRNA EMBL; BC063533; AAH63533.1; -; mRNA CCDS; CCDS10030.1; - RefSeq; NP_065104.1; NM_020371.2 UniGene; Hs.555966; - ProteinModelPortal; Q9NQS1; - BioGrid; 121366; 10 IntAct; Q9NQS1; 5 MINT; MINT-143075; - STRING; 9606.ENSP00000306822; - iPTMnet; Q9NQS1; - PhosphoSitePlus; Q9NQS1; - BioMuta; AVEN; - DMDM; 20454834; - EPD; Q9NQS1; - MaxQB; Q9NQS1; - PaxDb; Q9NQS1; - PeptideAtlas; Q9NQS1; - PRIDE; Q9NQS1; - Ensembl; ENST00000306730; ENSP00000306822; ENSG00000169857 GeneID; 57099; - KEGG; hsa:57099; - UCSC; uc001zhj.4; human CTD; 57099; - DisGeNET; 57099; - GeneCards; AVEN; - HGNC; HGNC:13509; AVEN HPA; HPA020863; - MIM; 605265; gene neXtProt; NX_Q9NQS1; - OpenTargets; ENSG00000169857; - PharmGKB; PA134874337; - eggNOG; ENOG410IKTA; Eukaryota eggNOG; ENOG4111U7Z; LUCA GeneTree; ENSGT00390000003299; - HOGENOM; HOG000231429; - HOVERGEN; HBG024370; - InParanoid; Q9NQS1; - OMA; WDRYQDI; - OrthoDB; EOG091G0N3H; - PhylomeDB; Q9NQS1; - TreeFam; TF332067; - BioCyc; ZFISH:ENSG00000169857-MONOMER; - GenomeRNAi; 57099; - PMAP-CutDB; Q9NQS1; - PRO; PR:Q9NQS1; - Proteomes; UP000005640; Chromosome 15 Bgee; ENSG00000169857; - CleanEx; HS_AVEN; - ExpressionAtlas; Q9NQS1; baseline and differential Genevisible; Q9NQS1; HS GO; GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell GO; GO:0005622; C:intracellular; IDA:UniProtKB GO; GO:0016020; C:membrane; IDA:UniProtKB GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB InterPro; IPR026187; Aven PANTHER; PTHR16524; PTHR16524; 1 1: Evidence at protein level; Apoptosis; Complete proteome; Membrane; Methylation; Phosphoprotein; Polymorphism; Reference proteome CHAIN 1 362 Cell death regulator Aven /FTId=PRO_0000064768 COMPBIAS 5 85 Ala/Gly-rich MOD_RES 94 94 Phosphoserine MOD_RES 230 230 N6-methyllysine VARIANT 228 228 Q -> R (in dbSNP:rs2241647) /FTId=VAR_020144 SEQUENCE 362 AA; 38506 MW; D86517BA087232D4 CRC64; MQAERGARGG RGRRPGRGRP GGDRHSERPG AAAAVARGGG GGGGGDGGGR RGRGRGRGFR GARGGRGGGG APRGSRREPG GWGAGASAPV EDDSDAETYG EENDEQGNYS KRKIVSNWDR YQDIEKEVNN ESGESQRGTD FSVLLSSAGD SFSQFRFAEE KEWDSEASCP KQNSAFYVDS ELLVRALQEL PLCLRLNVAA ELVQGTVPLE VPQVKPKRTD DGKGLGMQLK GPLGPGGRGP IFELKSVAAG CPVLLGKDNP SPGPSRDSQK PTSPLQSAGD HLEEELDLLL NLDAPIKEGD NILPDQTSQD LKSKEDGEVV QEEEVCAKPS VTEEKNMEPE QPSTSKNVTE EELEDWLDSM IS
Research Areas
Citations (0)

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Background

Protects against apoptosis mediated by Apaf-1.

References

Chau B.N.,et al.Mol. Cell 6:31-40(2000).
Olsen J.V.,et al.Cell 127:635-648(2006).
Dephoure N.,et al.Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Olsen J.V.,et al.Sci. Signal. 3:RA3-RA3(2010).

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$ 395.00
Cat# ALS11376
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