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>   home   >   Products   >   Primary Antibodies   >   TP1 / TEP1 Antibody (N-Terminus)   

TP1 / TEP1 Antibody (N-Terminus)

Rabbit Polyclonal Antibody

     
  • IF - TP1 / TEP1 Antibody (N-Terminus) ALS11487
    Immunofluorescence of TP-1 in Human Lung cells with TP-1 antibody at 20 ug/ml.
  • WB - TP1 / TEP1 Antibody (N-Terminus) ALS11487
    Western blot of TP1 in human kidney tissue lysate with TP1 antibody at (A) 1 and (B) 2 ug/ml.
  • IHC - TP1 / TEP1 Antibody (N-Terminus) ALS11487
    Anti-TEP1 antibody IHC of human skin.
  • IHC - TP1 / TEP1 Antibody (N-Terminus) ALS11487
    Anti-TEP1 antibody IHC of human breast.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF
Primary Accession Q99973
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 290kDa
Dilution IHC-P (5 µg/ml)
Additional Information
Gene ID 7011
Other Names Telomerase protein component 1, Telomerase-associated protein 1, Telomerase protein 1, p240, p80 telomerase homolog, TEP1, TLP1, TP1
Target/Specificity 20 amino acid peptide from near the amino terminus of human TP1.
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
PrecautionsTP1 / TEP1 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TEP1
Synonyms TLP1, TP1
Function Component of the telomerase ribonucleoprotein complex that is essential for the replication of chromosome termini. Also component of the ribonucleoprotein vaults particle, a multi- subunit structure involved in nucleo-cytoplasmic transport. Responsible for the localizing and stabilizing vault RNA (vRNA) association in the vault ribonucleoprotein particle. Binds to TERC (By similarity).
Cellular Location Nucleus. Chromosome, telomere.
Tissue Location Ubiquitous..
Citations (0)

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Background

Component of the telomerase ribonucleoprotein complex that is essential for the replication of chromosome termini. Also component of the ribonucleoprotein vaults particle, a multi- subunit structure involved in nucleo-cytoplasmic transport. Responsible for the localizing and stabilizing vault RNA (vRNA) association in the vault ribonucleoprotein particle. Binds to TERC (By similarity).

References

Harrington L.,et al.Science 275:973-977(1997).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Harrington L.,et al.Genes Dev. 11:3109-3115(1997).
Kickhoefer V.A.,et al.J. Biol. Chem. 274:32712-32717(1999).
Beattie T.L.,et al.Mol. Biol. Cell 11:3329-3340(2000).

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$ 395.00
Cat# ALS11487
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