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>   home   >   Products   >   Primary Antibodies   >   Neuroscience   >   SLIT1 Antibody (aa487-504)   

SLIT1 Antibody (aa487-504)

Rabbit Polyclonal Antibody

     
  • IHC - SLIT1 Antibody (aa487-504) ALS11540
    Anti-SLIT1 antibody IHC of human kidney.
  • IHC - SLIT1 Antibody (aa487-504) ALS11540
    Anti-SLIT1 antibody IHC of human pancreas.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession O75093
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 168kDa
Dilution ELISA (1:10000-1:50000), IHC-P (5 µg/ml), WB (1:500-1:2000)
Additional Information
Gene ID 6585
Other Names Slit homolog 1 protein, Slit-1, Multiple epidermal growth factor-like domains protein 4, Multiple EGF-like domains protein 4, SLIT1, KIAA0813, MEGF4, SLIL1
Target/Specificity SLIT-1 protein
Reconstitution & Storage +4°C or -20°C, Avoid repeated freezing and thawing.
PrecautionsSLIT1 Antibody (aa487-504) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SLIT1
Synonyms KIAA0813, MEGF4, SLIL1
Function Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions (By similarity). SLIT1 and SLIT2 together seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb.
Cellular Location Secreted.
Tissue Location Predominantly expressed in adult forebrain. Expressed in fetal brain, lung and kidney
Research Areas
Citations (0)

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Background

Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions (By similarity). SLIT1 and SLIT2 together seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb.

References

Itoh A.,et al.Brain Res. Mol. Brain Res. 62:175-186(1998).
Nakayama M.,et al.Genomics 51:27-34(1998).
Nakajima D.,et al.DNA Res. 9:99-106(2002).
Nakayama M.,et al.Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
Deloukas P.,et al.Nature 429:375-381(2004).

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$ 395.00
Cat# ALS11540
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